Incorporation of Tritiated Water (HTO) and Organically Bound Tritium (OBT) into Phospholipids and Gangliosides of Rat Brain

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概要

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• Three generations of rats were long-term exposed to HTO in drinking water at activity of 37.0 kBq/ml or to food containing OBT at activity of 48.1 kBq/g. The rats consumed tritiated water and tritiated food ad libitum. In the experiment the F_1 and F_2 generation of rats were exposed continuously from conception to the 21-st or 120-th day of age and rats of F_3 generation during 22 days of their intrauterine life. It was found that the amount of tritium incorporated into the major rat brain phospholipids and gangliosides after administration of tritiated food was higher than after administration of tritiated water. Tritium activity in all studied phospholipids and gangliosides was the highest in 21-day-old rats exposed during both-pregnancy and lactation.

• 日本放射線影響学会の論文

著者

• Kowalska M

  Central Laboratory For Radiological Protection

• Kowalska Maria

  Central Laboratory For Radiological Protection

関連論文

• Incorporation of Tritiated Water (HTO) or Organically Bound Tritium (OBT) into Ammo Acids of Rat Brain Proteins
• Incorporation of Tritiated Water (HTO) and Organically Bound Tritium (OBT) into Phospholipids and Gangliosides of Rat Brain

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