Induction of Prophages in Spores of Bacillus subtilis by Ultraviolet Irradiation from Synchrotron Orbital Radiation1
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概要
- 論文の詳細を見る
SR UV/Spore/Prophage Prophages were induced from Bacillus subtilis spores lysogenic with SPO2 by ultraviolet (160 nm to 240 nm) irradiation from synchrotron orbital radiation (SR UV). SR UV at around 220 nm was most effective in the inactivation of spores and prophage induction from lysogenic spores, suggesting that the lesions are produced on the DNA molecule which eventually induces signals to inactivate the phage repressor. Prophages can be induced by various kinds of treatments which generally arrest chromosomal replication in bacterial cells. Signals, not identified yet, resulting from DNA degradation during repair of damages, activate some cellular components which then inactivate the phage repressor1). Therefore phage inducing agents must primarily damage cellular DNA. Bacillus sub tilis is the genetically best studied microorganism among those forming spores and can harbor prophages in a spore state. So far, no report could be found concerning prophage induction in spores of microorganisms including Bacillus subtilis.
- 日本放射線影響学会の論文
著者
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Ohta Y.
Department of Physics, Chiba University
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ITO T.
Institute of Physics, Graduate School of Arts and Sciences, Univ.of Tokyo
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Hieda K.
Faculty Of Sciences Rikkyo University
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SADAIE Y.
Department of Induced Mutation, National Institute of Genetics
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KADA T.
Department of Induced Mutation, National Institute of Genetics
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KOBAYASHI K.
Institute of Biological Sciences, University of Tsukuba
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Sadaie Y.
Department Of Induced Mutation National Institute Of Genetics
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Kada T.
Department Of Induced Mutation National Institute Of Genetics
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Kobayashi K.
Institute for Chemical Research, Kyoto University
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