Cataracts

概要

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Several months to years after exposure to ionizing radiation of the atomic bombs (A-bombs), some survivors developed cataracts. The characteristic clinical finding was a localized lenticular opacity on the inner surface of the posterior polar capsule presenting a polychromatic sheen, and punctate opacities or aggregations thereof in the subcapsular cortical layer of the posterior polar region. In the majority of the affected survivors, the degree of opacification of these radiation cataracts was minimal to moderate and remained unchanged. These cases had no other subjective disturbances associated with this condition. The visual organ exposed to the atomic bombs was subject to burns, and mechanical and radiation injuries. Of these, the radiation injuries of the lens posed the greatest late effect problem. Radiation cataract was the first late effect documented as occurring among those exposed to the atomic bombs. Reports of such cataracts among survivors were made by Hirose and Fujino in September 1949 and by Cogan, Martin and Kimura in December 1949. Subsequent ophthalmologic studies of survivors were performed at the Atomic Bomb Casualty Commission (ABCC) by Cogan, Martin, Kimura and lkui (1950), Fillmore (1952), Sinskey (1955), Hall et al (1964), and by Miller et al (1967, 1968). Many surveys for such abnormalities were also conducted by Japanese ophthalmologists.
日本放射線影響学会の論文