Change in Radiosensitivity on the Development of Sea Urchin Eggs during the Early Cleavage Stage II. Protection against X-ray lrradiation by Cysteamine

スポンサーリンク

概要

• 論文の詳細を見る

• The effect of cysteamine on the fiuctuation of X-ray sensitivity during early cleavage stage of sea urchin eggs expressed by pluteus formation rate was examined. Sea urchin eggs were very resistant to radiation immediately after insemination or after S phase of the cleavage. When irradiation was given just prior to S phase or in the phase of cytokinesis, the eggs were very sensitive. In these sensitive stages, existence of cysteamine during X-irradiation apparently protected eggs against radiation effect. Dose modifying factor increased linearly from 1.8 to 3.4 with increasing dose of cysteamine (25 mM-75 mM) added. In a previous paper the present author has reported that the radiosensitivity expressed by the pluteus formation rate (PFR : the rate of the eggs which could develop into the pluteus larval stage) fluctuated periodically during the early cleavage cycle of sea urchin eggs. The PFR of sea urchin eggs was as high as that of the nonirradiated control group when they are irradiated with 500 or 1,000 R of X-rays at the stage immediately after insemination, and also after the Ist S phase.

• 日本放射線影響学会の論文

著者

• 中村 泉

  東京大学理学部動物学教室

関連論文

• Change in Radiosensitivity on the Development of Sea Urchin Eggs during the Early Cleavage Stage II. Protection against X-ray lrradiation by Cysteamine
• "Indent" Formation and Mitotic Delay of Sea Urchin Eggs Fertlllzed with X-irradiated Sperms

スポンサーリンク