錠剤の圧縮成形における放出条件と錠剤内部構造について

概要

論文の詳細を見る
There are few reports published on the state of pore distribution in tablets. Using a tablet machine and a compression testing instrument, the relation between the ejecting conditions and the pore distribution of tablets has been 'investigated and the following conclusion was obtained. The total volume of pores having 10^3〜10^4Å radius in the center of tablets was greater than that in the edge of tablets. Furthermore the similar phenomenon was observed when the powder was slowly compacted and then subjected to tensile stress. As for the tablets with less capping tendency, the total volume of pores in the center of tablets was comparatively reduced when the tablets were ejected with the suitable compressing force retained. Consequently, the effect of applied force was considered to give sufficient relaxation of stress, such as tensile stress, to the tablet during ejection.
社団法人日本材料学会の論文
1976-07-15