Diffusion-Weighted Echo Planar Imaging of Acute Brain Infarction:a Oreliminary Report

概要

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The clinical usefulness of diffusion-weighted echo planar imaging(DW-EPI)was studied in 55 patients with acute brain ischemia.Ischemic lesions were identified on DW-EPI as hyperintense regions in all patients before changes were detected by conventional magnetic resonance imaging techniques in 12 cases studied earlier than 6 hours after onset.The earliest case was verified on DW-EPI at 50 minutes after onset.The ultra-fast imaging technique took less than 2 minutes to perform even for restless patients.Three patients had cardioembolic middle cerebral artery occlusion,and emergent percutaneous transluminal recanalization was carried out.Chronological changes in the signal of brain ischemia on DW-EPI depended on the site and size of the lesion,lacunar infarct of basal ganglia,and/or massive infarct due to major vessel occlusion,and were affected by associated hemorrhagic events.Coronal DW-EPI could more easily demarcate ischemia in the brainstem and/or cerebellum than axial scans when susceptibility artifacts were present.Coronal scans also demonstrated the site and direction of the pyramidal tract and its anatomical correlation with the lesions.DW-EPI has potential for the diagnostic and therapeutic planning of patients with acute brain ischemia.
日本脳神経外科学会の論文
1999-12-15