Hydrolytic Enzymes (Acid Phosphatase and Beta-glucuronidase) in Cultured Brain Tumors

概要

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A histochemical study of hydrolytic enzymes such as acid phosphatase and beta-glucuronidase was made on cultured brain tumor cells. Well-differentiated astrocytic cells, oligodendroglioma cells, and medulloblastoma cells showed low activities. Migrating cells and macrophage-like cells showed intense activities. Meningioma cells and schwannoma cells showed relatively intense activities at the early stage of cultivation. At the aged stage, the former showed a characteristic pattern of reaction products. The intensity and distribution of beta-glucuronidase were similar to those of acid phosphatase in cultured brain tumors. The relationship of hydrolytic enzymes to cellular differentiation and viability was discussed.
日本脳神経外科学会の論文
1984-07-15