単発性頭蓋内形質細胞腫

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Although plasma-cell tumors are usually multiple and located in the bones, the occurrence of a single plasmacytoma in the soft tissue has been reported. However, only 13 cases of solitary intracranial plasmacytoma has been reported. This report describes such a case which was recently experienced. The patient was a 45 year-oldman who was admitted because of visual disturbance and mild left hemiparesis. Neurological examination revealed bilateral choked discs, left homonymous hemianopsia and mild left hemiparesis. Laboratory examinations were within normal limits. Bone X-ray films and scintigraphy of the whole body showed no abnormalities. Bence-Jones proteinuria, hyperproteinemia and abnormal plasma cells in the bone marrow were not found. The absence of abnormal protein in the serum and urine was confirmed by immunoelectrophoretic examination. Right carotid angiography revealed a homogeneous vascular stain in the parieto-occipital area in the late arterial phase. ^<99m>Tc brain scan showed a hot area in the same location. Cranial CT scan showed a low density area which was surrounded by an irregular-shaped high density area in the parieto occipital lobes. This was subtotally resected. The tumor was not attached to the dura mater. Histopathological examination of the tumor revealed a typical plasmacytoma. In the cytoplasm of the tumor cells, Ig-M was detected by the enzyme labeled antibody method. The postoperative course was uneventful. A short review of the world literature concerning diagnosis, treatment and prognosis of solitary intracranial plasmacytomas is included.
日本脳神経外科学会の論文
1981-03-15

単発性頭蓋内形質細胞腫

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