クモ膜下出血後の脳血管攣縮時における血管内因子の検索 : 血小板および血液凝固機能を中心として

概要

論文の詳細を見る
Cerebral vasospasms with subsequent infarction have an important effect on the outcome of patients with ruptured intracranial aneurysms. Clinical and experimental studies of intravascular factors in the pathogenesis of cerebral infarctions, with particular regard to platelets and coagulation factors, were performed. In these studies, a systemic hypercoagulable state and platelet hyperactivity were observed, and in the experimental study, crenated red blood cells were seen in the course of vasospasms. These systemic changes in intravascular components are thought to accelerate carebral ischemia through an increase in blood viscosity, microthrombosis, and reduced deformability of red cells.
日本脳神経外科学会の論文
1980-05-15