Effect of Thyrotropin-releasing Hormone on Na^+-K^+-Adenosine Triphosphatase Activity Following Experimental Spinal Cord Trauma
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概要
- 論文の詳細を見る
The effect of thyrotropin-releasing hormone (TRH) on spinal cord Na^+-K^+-adenosine triphosphatase (Na^+-K^+-ATPase) activity after spinal cord injury was evaluated in rats. The rats were injured by compression of the cord at T-10 for 1 minute with a 50-g clip. Saline in the placebo group (n = 8) and TRH (0.6 mg per dose) in the TRH group (n = 9) were administered intraperitoneally as bolus injections in two doses, at 45 and 120 minutes after the injury. The Na^+-K^+-ATPase activity level in the TRH group was significantly higher (p = 0.024) than in placebo group. These results indicate a possible role for TRH treatment in spinal cord injury.
- 日本脳神経外科学会の論文
- 1996-05-15
著者
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Ceylan Savas
Department Of Neurosurgery School Of Medicine Kocaeli University
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Akturk Fadil
Departments Of Neurosurgery School Of Medicine Black Sea Technical University
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Deger Orhan
Departments Of Biochemistry School Of Medicine Black Sea Technical University
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Deger Orhan
Department Of Biochemistry Faculty Of Medicine Karadeniz Technical University
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Usul Haydar
Department Of Neurosurgery Karadeniz Technical University School Of Medicine
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Usul Haydar
Departments Of Neurosurgery School Of Medicine Black Sea Technical University
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BAYKAL Suleyman
Departments of Neurosurgery, School of Medicine, Black Sea Technical University
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Baykal Suleyman
Departments Of Neurosurgery School Of Medicine Black Sea Technical University
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Baykal Suleyman
Department Of Neurosurgery Karadeniz Technical University School Of Medicine
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