初回手術後15年目の晩期再発と乳癌の続発を伴った卵巣顆粒膜細胞腫の1例

概要

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A case of granulosa cell tumor of the ovary which lately recurred 15 years after the first surgical treatment, and associated with subsequent co-occurrence of breast cancer was reported. On the first occasion, a 39-year-old gravid 1, para 0 housewife was referred to our hospital because of genital bleeding which had continued on and off since 5 years ago. Under a diagnosis of solid ovarian tumor, left salpingooophorectomy and wedge resection of the right ovary were done. Adult-type granulosa cell tumor of the left ovary with no malignant cells in the right ovary was diagnosed. Fifteen years later the patient was referred to our hospital again because of abnormal genital bleeding. Laparotomy was performed and late recurrence of granulosa cell tumor was diagnosed. Two years after the second laparotomy, breast cancer was diagnosed and radical mammectomy was performed. The present report emphasizes that in case of granulosa cell tumor, long-term follow up for recurrence of primary tumor as well as careful examination for the occurrence of second primary tumor in estrogen target organs such as the breasts and endometrium are important.
社団法人日本産科婦人科学会の論文
2001-08-01