PHAGOCYTOSIS OF HUMAN CYTOTROPHOBLAST CELL INVADING INTO DECIDUAL TISSUE IN EARLY STAGE OF GESTATION

概要

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To elucidate the mechanism of trophoblastic invasion, further electron microscopic observation of human implantation sites, described in a prelirpinary paper, were performed. The cytotrophoblast cells invaded decidual tissue have taken ih many cells and absorbed many materials. In this paper, the authors specifically report the phagocytotic function of the cytotrophoblast cell. It was clarified by criteria, described in preliminary papers, for judgement of cells composing the feto-maternal junctional zone that almost all cells phagocytized by the cytotrophoblast cells were decidual cells which showed significant ultrastructural changes in various degrees; some cells still had intrinsic features by which the cells could be clearly identified as decidual cell, and some cells were considered as a strongly altered degenetated=decidual cells. Moreover, even though these phagocytized cells had not so many lysosome that these cells can autolysis, the cytotrophoblast cells had many lysosome having strong activity of acid phosph,atase. After the cytotfophoblast cells contact decidual cells by means of nlany patterns, the cytotrophoblast cells can phagocytized the inactivated cell and can intracytoplasmically digest the cell actively.
社団法人日本産科婦人科学会の論文
1981-04-01