SHORT TERM RESULTS OF LIVING RELATED LIVER TRANSPLANTATION(招待講演VII ,第29回日本小児外科学会総会)

概要

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A program in living related liver transplantation was initiated at the University of Chicago in 1989. The initial protocol studied 21 consecutive children receiving 23 living related liver transplants during a 14 month period. This initial series demonstrated that the donor operation could be performed safely and that patient and graft survival were 80 and 70 percent respectively. Based on this initial experience accumulated in our hospital, we have initiated a program in which living related liver transplantation is offered as a routine option for children requiring liver transplantation. Since this initial series, 19 patients have received liver grafting, with a live donor accounting for 40 percent of the patients transplanted during this period. Of this series, 18 of 19 patients are alive between and 3 and 12 months post transplantation. A single patient died due to septic complications of unsuccessful treatment for rejection. Two other liver grafts were replaced successfully due to arterial thrombosis. All donors have fully recovered and no chronic health problems have been observed in a total of 42 donors in the entire series. We propose that liver related transplantation is a feasible technique yielding extremely high patient and graft survival and that it offers an acceptable option for the alleviation of the shortage of liver donors.
特定非営利活動法人日本小児外科学会の論文
1993-02-20