新生児期に腎不全で発症し,逆流防止術を施行した一側 VUR,他側低形成腎の2例

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Anti-reflux surgery for two infants with unilateral vesico-ureteral reflux (VUR) was performed to prevent the development of reflux nephropathy. The first case, two-day-old male, was admitted to our hospital for the purpose of operation for atresia ani. At the age of 9 day-old, it was recognized that his renal function was sevesely impaired. By voiding cystourethrogram, the diagnosis of VUR (grade III) on the right side with left renal hypoplasia was made. To promote the normal growth of the right kidney, anti-reflux surgery according to Cohen's method was performed at the age of 97 day-old. His total renal function has remained stable after the surgical intervention. The second case was a 3 day-old male and admitted to our hospital because of poor sucking. Investigation revealed depressed renal function. With further examination, the diagnosis of left VUR (grade V) and right renal hypoplasia was made. Low protein diet (1.5-2.0g/kg/day) has been started to lower the osmolar loading. For the same reason as the first case, an anti-reflux surgery according to Cohen's method was performed at the age of 74 day-old. His renal function improved dramatically after the surgery. And he was discharged from our hospital at the age of 116 day-old. These cases might suggest that an early surgical intervention and low protein diet lead to excellent recovery of renal function in patients with congenital urinary tract anomalies.
日本小児外科学会の論文
1989-08-20

新生児期に腎不全で発症し,逆流防止術を施行した一側 VUR,他側低形成腎の2例

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