多毛症の診断と治療(内分泌)

概要

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The excess hair growth is more often observed in the Caucasian than in the Mongolian. Japanese women much less complain of it, yet the necessity of treatment depends upon the individual judgement over the hirsutism scoring after excluding the causative disorders. Hirsutism, androgenic, is differentiated from hypertrichosis, non-androgenic. The causes of excess hair growth are classified as follows ; physiological, ovarian, adrenal, metabolic and iatrogenic. The goal of treatment is to interrupt the steps leading to the increased androgen expression of the pilosebaceous unit, yet mechanical hair removal is practically necessary for cosmetic. he treatment consists of medical and surgical approaches reducing androgen excess, and weight loss. The medical treatment consists of ovarian targetted drugs (pills, synthetic progestins or GnRH analogues), adrenal targetted drugs (glucocorticoids), anti-androgenic drugs and insulin sensitizers. Those drugs are not approved for the treatment of hirstism in Japan, being able to be used for the treatment of adapted disorders with coexistent hirsutism. The operative treatment consists of removal of ovarian and adrenal tumors and wedge resection/electrocautery of polycystic ovavies.
社団法人日本産科婦人科学会の論文
2003-08-01