小児外科疾患における DIC と交換輸血療法について

概要

論文の詳細を見る
We experienced 70 pediatric surgical cases of DIG from 1978 to 1985. The purposes of this paper is to analyse their clinical features and examine whether or not exchange transufusion is an effective measure against DIG. Premature babies and neonates had fallen in DIG easier (17.7%) and shown much higher mortality rate (80.6%) than others. The main trigger of DIG was bacterial sepsis due to E. coli, P. aeruginosa and klebsiella. Respiratory insufficiency and renal failure were common symptoms and became the cause of death. Hepatic, cardiac failure and subcutaneous hemorrhagic tendency were rare. Exchange transfusion revealed highest survival rate (61%) compared with other treatment (Heparin, FOY etc.) (13.5%). Our results examined prior to exchange transfusion demonstrated that several factors (the presence of 50% reduction of platelet count within one day, the presence of MOF more than 2 organs, anuria, serum pH 7.30, BE-10) were the markedly poor prognostic signs.
日本小児外科学会の論文
1986-11-02