新生児外科領域におけるCatheter-related sepsis症例の検討 : とくに血小板減少との関連について

概要

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Total Parenteral Nutrition (TPN) has provided a great progress in neonatal surgery, however catheter-related sepsis still remains unsolved. Of 69 surgical neonates receiving TPN from November 1982 to October 1983, 10 cases were diagnosed as a catheter-related sepsis. Catheter-related sepsis was defined as an episode of sepsis resolved by removal of cather followed by associated therapies. Serial platelet count, leukocyte count, CRP and coagulation studies (PT, PTT, Fibrinogen) were performed before and after removal of catheter. Thrombocytopenia less than 100,000/mm^3 was found in 7 cases and sudden fall of platelet count was found in another 3 cases. Leukocyte count and coagulation studies did not correlate with platelet count. Thrombocytopenia, particulary sudden fall of platelet count is considered to be useful for the early identification of catheter-related sepsis in neonates.
1984-12-20