急激な臨床経過を辿った小児胸腺腫の1例と本邦報告例の検討

概要

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A l-year-7-month-old girl with dyspnea and cyanosis was admitted. Because of respiratory distress due to the large anterior mediastinal mass, emergent operation was performed and the mediastinal tumor was extirpated subtotally. Histologically, it was diagnosed as malignant thymoma of epithelial type. Radiation therapy to the anterior mediastinum and intensive chemotherapy were given and the remission appeared to be obtained. However, relapse occurred with rapid progression and the tumor showed no response to the anticancer drugs. The patient died 3 months after operation. The case presented here showed that the rapidly progressive clinical course is that must serious problem in the therapy of thymoma in childhood. 34 cases of thymoma under 15 years of age, including our case, were collected from Japanese literatures and reviewed. By analysis of them the preoperative chemotherapy or radiation therapy seemed to be effective for the advanced thymoma.
日本小児外科学会の論文
1983-06-20