幼小児手術後における細胞性免疫能の変化についての研究
スポンサーリンク
概要
- 論文の詳細を見る
Postoperative changes of cellular immunity were studied in 90 infants and children. Thirty-one patients were between one and six months of age, of whom 10 underwent operation for inguinal hernia or other minor procuderes, 16 minor abdominal surgery and 5 surgery for obstructive jaundice. Thirty patients were between 7 months and 3 years of age, of whom 13 underwent operation for inguinal hernia or other minor procedures, 6 minor abdominal surgery and 11 major abdominal surgery. Twenty-nine patients were above 3 years of age, of whom 21 underwent operation for inguinal hernia or other minor procedures and 8 major abdominal surgery. Sixty-seven patients were studied before and after operation and 7 non-surgical patients were also studied as age-matched control, PHA skin test, PHA induced lymphocyte transformation index, number of lymphocytes, T-cell % and number of T-cell were examined as parameters of cellular immunity. The present studies provided the following results; 1. There were changes of cellular immunity proportional to the age at the time of the examinations. PHA skin test showed significantly low value in the younger infants. 2. There was no significant change of cellular immunity after operation for inguinal hernia or other minor procedures in all age groups. 3. There was no significant change of cellular immunity after minor abdominal surgery in both younger and older infants. 4. Slight decrease of cellular immunity was found in younger children after major abdominal surgery, but the recovery was noted in the early postoperative period. 5. Changes of cellular immunity in older children after major abdominal surgery were similar to those seen in adults after a subtotal gastrectomy. 6. Cellular immunity of infants with obstructive jaundice improvd markedly afte disappearance of jaundice by the operation.
- 特定非営利活動法人日本小児外科学会の論文
- 1981-12-20