EFFECT OF BODY IRON STORES ON INDICES OF BIOSYNTHESIS AND DESTRUCTION OF RED BLOOD CELLS AFTER A SINGLE SESSION OF CYCLING EXERCISE
スポンサーリンク
概要
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Objectives: The present study investigates the effects of body iron stores upon indices of biosyn-thesis and destruction of red blood cells (RBC) induced by a single session of cycling exercise. Design: Eight sedentary female students were divided into groups depending on their body iron stores: normal (C group, n=5) and iron deficient (D group, n=3). Blood samples were collected at five time points of before (pre), immediately after (0 hours), then 1, 3 and 6 hours after exercise (248±31 kcal, 70% VO_2 peak level). Osmotic fragility and serum haptoglobin (hp) concentration served as of for degradation, and δ-aminolevulinate dehydratase (ALAD) activity, erythropoietin concentration and number of reticulocytes served as indices of RBC biosynthesis. Results: A single session of cycling exercise did not affect the level of RBC, hemoglobin, hematocrit, serum iron, ferritin, transferrin saturation, hp and osmotic fragility in either groups. The δ-ALAD activity increased at 3 (p<0.05) and 6 hours (p<0.01) after exercise compared with that at 0 hours in the C group. In contrast, δ-ALAD activity in the D group was significantly lower at 3 hours after exercise than that of C group (p<0.001). Reticulocytes and erythropoietin concentration increased gradually in the C group after exercise, but not in the D group. Conclusions: A single session of cycling exercise under our experimental conditions enhanced RBC biosynthesis indicated by δ-ALAD activity, whereas exercise-induced hemolysis was not evident. Body iron stores affect the δ-ALAD activity induced by a single bout of cycling exercise.
- 2002-04-16
著者
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Mekata Yuko
スポーツ栄養学研究会(日本女子体育大学内)
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Kawano Yukari
日本女子体育大学:スポーツ栄養学研究会(日本女子体育大学内)
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TOKASHIKI AKIKO
東京都神経科学総合研究所
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HAYASHI KEIKO
スポーツ栄養学研究会(日本女子体育大学内)
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MATSUMOTO HARUMI
千葉西総合病院
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UCHIYAMA IWAO
京都大学大学院工学研究科環境工学専攻