INFLUENCE OF MODERATE EXERCISE OF RAT ON CARBOHYDRATE AND LIPID METABOLISM

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概要

• 論文の詳細を見る

• Adult male rats were made to run until exhaustion (54-114min) at a speed of 25m/min. They were sacrified at rest, 5, 15, 30, 45min and exhaustion of exercise, and blood glucose and blood lactate concentration as well as glycogen, FFA and triglyceride contents in the myocardium, liver and gastrocnemius muscle were determined. Changes of these substances were significant during exercise, despite of running at a constant speed. Blood glucose and liver glycogen were increased as late as 30min of exercise, and in association with this, blood lactate gradually increased. Glycogen reduction in the working gastrocnemius muscle was small. These observations within the initial 30min of exercise suggest that the activity of the glycogen synthesis system in the organs may be enhanced during exercise. At 45min, however, liver and muscle glycogen level abruptly dropped with exception of the myocardial content. This was especially prominent in the skeletal muscle, manifesting an anaerobic state, which is characteristic of lactate production and lowered oxygen consumption in the exercised muscle. Conversely to such depletion of the carbohydrate energy source, FFA concentration was concurrently elevated in all the examined tissues and organs, and this was intimately related with the duration of exercise. During the exercise, triglyceride content declined in plasma, myocardium and skeletal muscle, and especially in the former two, marked decline commenced at the start of exercise. Abrupt fall in myocardial FFA and triglyceride levels in the first 15min of exercise suggests that the lipids may be predominantly used as the energy source of the myocardium from the start of exercise.

• 日本体力医学会の論文
• 1975-12-01

著者

• Harada Kunihiko

  Department Of Mathematical Informatics Graduate School Of Information Science And Technology The Uni

• Harada Kunihiko

  Department Of Physiology The Jikei University School Of Medicine

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