脳性麻痺に対するCercineの効果

概要

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In treatment of the patient with cerebral palsy, training is most important. The appearance of a medical compound from which we can expect progress in the training effect was very desirable.Cercine was given to seventeen patients with cerebral palsy of the spastic type and mixed type with athetosis which have strong muscle spasmus. Of the seventeen patients nine were of spastic type and eight were of mixed type with athetosis.Excellent result was obtained in fifteen patients.Decrease of muscle spasmus and opisthotonus, possibility of turning over in bed and maintenance of sitting, improvement of walking were aquired. Namely muscle relaxation was remarkable.In mixed type with athetosis in which muscle spasmus was light, results were not effective.Dose was very different owing to symptom and individual differences.Dose of one day is generally as follows : infants : 1〜2mg.child : 2〜6mg.adolescent : 6〜10mg.Treatment of cerebral palsy needs a very long period of time as compare with general orthopaedic diseases.Effects of cercine are muscle relaxation, anticonvulsion and sedative action. These combined actions have many more enhanced effects.The Use of cercine has great significance for the treatment of cerebral palsy.In the future, it is believed that cercine will fulfils an important part in the treatment of the cerebral palsy.
社団法人日本リハビリテーション医学会の論文