ANALYSIS OF QUANTITATIVE DATA OBTAINED FROM TOXICITY STUDIES SHOWING NON-NORMAL DISTRIBUTION
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概要
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The data obtained from toxicity studies are examined for homogeneity of variance, but, usually, they are not examined for normal distribution. In this study I examined the measured items of a carcinogenicity/chronic toxicity study with rats for both homogeneity of variance and normal distribution. It was observed that a lot of hematology and biochemistry items showed non-normal distribution. For testing normal distribution of the data obtained from toxicity studies, the data of the concurrent control group may be examined, and for the data that show a non-normal distribution, non-parametric tests with robustness may be applied.
- 日本トキシコロジー学会の論文
- 2005-05-25
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関連論文
- EVALUATION OF TOXICITY DOSE LEVELS BY CLUSTER ANALYSIS
- ANALYSIS OF QUANTITATIVE DATA OBTAINED FROM TOXICITY STUDIES SHOWING NON-NORMAL DISTRIBUTION