MUTAGENICITY STUDIES WITH PALM FRUIT CAROTENE

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概要

• 論文の詳細を見る

• The mutagenicity of palm fruit carotene was examined using the reverse mutation test with bacteria, the chromosomal aberration test with mammalian cells and the micronucleus test in mice. The carotene induced neither reverse mutation in Salmonella typhimurium TA98, TA1537, TA100, TA1535 and in Escherichia coli WP2uvrA, nor structural and numerical (polyploidy) chromosomal aberrations in the Chinese hamster fibroblast cell line (CHL). In addition, no increase in micronucleated polychromatic erythrocytes was elicited in the micronucleus test in CD-1(ICR) male mice. It is concluded that palm fruit carotene had no mutagenic activity in these in vitro and in vivo tests.

• 日本トキシコロジー学会の論文
• 1995-11-25

著者

• Nakamura Tsuneaki

  Human & Environmental Safety Evaluation Center, LION CORPORATION

• Nakamura Tsuneaki

  Human Safety Evaluation Center Research And Development Headquarters Lion Corporation

• Masuda Mitsuteru

  Human Safety Evaluation Center Lion Corporation

• Masuda Mitsuteru

  Human Safety Evaluation Center Research And Development Headquarters Lion Corporation

• HARESAKU Mitsuru

  Human Safety Evaluation Center, Research and Development Headquarters, Lion Corporation

• TAKEI Toshiharu

  Human Safety Evaluation Center, Research and Development Headquarters, Lion Corporation

• Takei Toshiharu

  Human Safety Evaluation Center Research And Development Headquarters Lion Corporation

• Haresaku Mitsuru

  Human Safety Evaluation Center Research And Development Headquarters Lion Corporation

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