ELECTRON MICROSCOPIC OBSERVATION ON DARK ENDOTHELIAL CELLS IN ERYTHEMA NODOSUM-LIKE LESIONS OF BEHCET'S DISEASE WITH ULTRASTRUCTURAL X-RAY SPECTROANALYSIS
スポンサーリンク
概要
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We used electron microscopy and electron microscopic X-ray spectroanalysis to examine the biopsies taken from erythema nodosum-like lesions of 20 patients with Behcet's disease. Electron-dense degenerated endothelial cells were found in the microcirculatory beds of the dermis and subcutaneous fat. However, electron microscopic X-ray spectroanalysis failed to demonstrate the localization of either chlorine or base metals in those degenerated endothelial cells. Moreover, neither in ultra-structurally normal endothelial cells, nor in infiltrating macrophages of erythema nodosum-like lesions the positive deposit of chlorine or base metals could not be detected. The results of this analysis suggest that environmental factors do not play an etiologic role in this disease. Significance of the degeneration of endothelial cells is not clear present.
- 日本トキシコロジー学会の論文
- 1987-08-25
著者
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Bang Dongsik
韓国
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BANG Dongsik
Department of Dermatology, Yonsei University College of Medicine
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Bang Dongsik
Department Of Dermatology Yonsei University
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Lee Sungnack
Department Of Dermatology Ajou University School Of Medicine
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Lee Sungnack
Department Of Dermatology Yonsei University College Of Medicine
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Lee Sungnack
Department Of Dermatology Ajou University Medical School Suwon Republic Of Korea
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UEKI Hiroaki
Department of Dermatology, Kawasaki Medical School
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HONMA Takayoshi
Department of Pharmacology, Kawasaki Medical School
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SAITO Taiich
Department of Pharmacology, Kawasaki Medical School
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NAKAGAWA Shojiro
Department of Dermatology, Kawasaki Medical School
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Nakagawa Shojiro
Department Of Dermatology Kawasaki Medical School
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Saito Taiich
Department Of Pharmacology Kawasaki Medical School
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Ueki Hiroaki
Department Of Dermatology Kawasaki Medical School
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Honma Takayoshi
Department Of Pharmacology Kawasaki Medical School
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