A COMPARATIVE STUDY ON THE EFFECTS OF PARAQUAT AND DIQUAT ON CULTURED HUMAN CELLS

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概要

• 論文の詳細を見る

• The effects of paraquat on human embryonic somatic cells were compared with those of diquat, which is a bipyridylium compound similar to paraquat. Cell lesions, mainly fatty degeneration, were observed after staining with Sudan Black B. Both herbicides caused fatty degeneration in the cells even at a concentration of 1 ppm; paraquat also caused more vacuolar degeneration at 200 to 400 ppm, than did diquat. Paraquat caused slightly higher lactate dehydrogenase activity than did diquat. The cell mortality was examined by staining with nigrosine and calculating the number of dead and damaged cells. The cell mortality for diquat was higher than that for paraquat at all concentrations but not significantly (p < 0.05).

• 日本トキシコロジー学会の論文
• 1981-08-25

著者

• 栗崎 恵美子

  福島県立医科大学法医学教室

• NAGAMORI Hajime

  福島県立医科大学法医学教室

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• A COMPARATIVE STUDY ON THE EFFECTS OF PARAQUAT AND DIQUAT ON CULTURED HUMAN CELLS

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