REPRODUCTION STUDY OF CARTEOLOL HYDROCHLORIDE IN MICE. PART 2. PERI- AND POSTNATAL TOXICITY.
スポンサーリンク
概要
- 論文の詳細を見る
Carteolol was orally administered to mice once a day at doses of 3, 30 and 150 mg/kg/day during the perinatal and lactation periods and evaluated on its adverse effects on pregnant animals and their offspring. No appreciably abnormal findings related to the drug administration were revealed. Therefore, it was concluded that carteolol have no serious toxic potential on parturition and lactation by mother animals, no adverse effects on growth and development, and behavioral and reproductive performance of offspring and no carcinogenic action through placental and milk transfer.
- 日本トキシコロジー学会の論文
- 1979-02-15
著者
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Tamagawa Minoru
Laboratories Of Biological Research Otsuka Pharmaceutical Co. Ltd.
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TANAKA Nobuyuki
Laboratories of Biological Research, Otsuka Pharmaceutical Co., Ltd.
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Nishino Hiroshi
Laboratories Of Biological Research Otsuka Pharmaceutical Co. Ltd.
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NUMOTO Toyoko
Laboratories of Biological Research, Otsuka Pharmaceutical Co., Ltd.
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Numoto Toyoko
Laboratories Of Biological Research Otsuka Pharmaceutical Co. Ltd.
関連論文
- Effects of Previous Experience on the Agonistic Behaviour of Male Crickets, Gryllus bimaculatus(Behavior Biology)
- REPRODUCTION STUDY OF CARTEOLOL HYDROCHLORIDE IN MICE. PART 1. FERTILITY AND REPRODUCTIVE PERFORMANCE.
- REPRODUCTION STUDY OF CARTEOLOL HYDROCHLORIDE IN MICE. PART 2. PERI- AND POSTNATAL TOXICITY.
- Local Innervation Patterns of the Metathoracic Flexor and Extensor Tibiae Motor Neurons in the Cricket Gryllus bimaculatus(Neurobiology)