フィブロネクチン点眼剤の保存方法の検討

概要

論文の詳細を見る
It was reported that fibronectin eyedrops facilitated healing trophic ulcer and recurrent corneal erosion. We studied effects of temperature, light, and material of container on the concentration of fibronectin. The decrement of fibronectin concentration at 4℃ was less than that at room temperature and 37℃. When fibronectin was placed in dark, the concentration decreased very slowly. A strong adsorption of fibronectin on the wall of glass vessel was observed, while little on the polypropylene or polyethylene container. These results suggest that fibronectin eyedrop preparation should be kept at 4℃ and in polypropylene or polyethylene container in dark.
日本医療薬学会の論文
1990-02-20