付着性・凝集性の大きい散剤の物性改良と分包誤差

概要

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Improvement on the physical properties of the following 4 samples, highly adhesive and agglutinative, was tried: Adsorbin, calcium lactate, Laxatol powder, and yokuinin extract powder, After adding magnesium stearate to the 4 samples, their packaging errors and recovery of weight after packing were determined with packaging machines having different valves (Konishi KC-747-K Type 12 with a plastic valve type 12 and with a stainless steel valve). In all the 4 samples, the packaging error was smaller with the machine having the plastic value than with a stainless steel. By addition of 0.4% magnesium stearate, the physical properties, packaging error and recovery of weight of Adsorbin were improved, thus suggesting that the method is useful for drug dispensing. An improvement on physical properties was also found in the remaining 3 samples, but no improvement on the packaging error and recovery of weight.
1986-06-20