カストロピロール(仔羊胃粘膜抽出製剤)のプロテアーゼ活性の安定性と配合変化
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概要
- 論文の詳細を見る
Compatibility of Gastropylore (GP, lamb's gastric mucosal extract) with other preparations was studied in terms of its residual protease activity. The admixtures were stored at relative humidity 75% and temperature 20°, and at 92% and 30°, respectively. The protease activity of GP, stored alone at RH 92% at30°, was stable for 2 weeks in spite of considerable damping. However, when GP was compounded with alkaline preparations, its protease activity became distinctly unstable after the storage at RH 92% at 30°. A statistically significant negative correlation was suggested between the basic degree of gradients and percentage of residual protease activity of the GP admixtures. It is not recommended that under the poor condition of moisture-proof GP is compounded with such antacids as sodium bicarbonate.
- 日本医療薬学会の論文
- 1980-08-20