坐剤の薬剤学的検討
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概要
- 論文の詳細を見る
Qualitative evaluation of suppositories was conducted by means of a simple test on in vitro disintegration time. Twenty kinds of commercial suppositories were selected as samples. Length and diameter of 20 each suppositories of the samples were measured with slide calipers. In the disintegration test, observation was continued for 6 hours on 10 suppositories of each sample soaked in the isotonic sodium chloride solution kept at a fixed temperature. Suppositories on hydrophobic bases were completely disintegrated within 20 minutes, and those on hydrophilic bases underwent a rapid change in the early stage but most of them did not show complete disintegration within the observation time.
- 日本医療薬学会の論文
- 1976-08-20