2 口腔扁平上皮癌におけるサイトケラチン19遺伝子の分子生物学的研究 (第462回大阪歯科学会例会)
スポンサーリンク
概要
- 論文の詳細を見る
In order to reserch the role of cytokeratin (CK) 19 gene expression in carcinogenesis, I investigated the effect of the expression of CK 19 gene in oral squamous cell carcinoma, epithelial dysplasia and normal gingiva. Total-RNA was extracted from biopsy materials and examined by revers transcription polymerase chain reaction (RT-PCR) and northern blot. The results showed that CK 19 mRNA expressed in every sample, and it was strongly positive in squamous cell carcinoma, moderately positive in epithelial dysplasia and slightly positive in normal gjngiva. These results jndicafes that CK 19 gene is an important factor of carcinogenesis in oral squamous cell epithelia.
- 大阪歯科学会の論文
- 1998-12-25