3 細菌内毒素の肉芽組織透過性からみた根尖病変の成立に関する実験的研究 : 皮下空気嚢の炎症性反応と透過性との関係 (第438回大阪歯科学会例会)

概要

論文の詳細を見る
I studied the ability of inflamed granulation tissue to prevent systemic diffusion of bacterial endotoxin in dental periapical lesions. Inflammatory reactions were induced in the wall of the subcutaneous air pouch of rats by administration of endotoxin. I then examined the endotoxin density of the circulating blood and the endotoxin volume of the air pouch fluid. Endotoxins were also injected intravenously in other rats. Endotoxins in the circulating blood decreased to normal levels more rapidly in the group injected in the air pouch than in the group injected intravenously. However, the endotoxin volume in the air pouch maintained a high level during all experimental periods. These results suggest that inflammatory tissue may act as a barrier to diffusion of endotoxins from the focus of a lesion to the body.
大阪歯科学会の論文
1994-12-25