1 人工骨移植材のヒト骨芽細胞様細胞に対する親和性 (第419回 大阪歯科学会例会)

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概要

• 論文の詳細を見る

• I cultured the cell line MG-63, which is derived from human osteosarcoma, and retains osteoblast characteristics, with and without hydroxyapatite (HAP). I examined the histocytochemistry, biosynthesis of the extracellular matrix of fibronectin, type I and type III collagen, and osteocalcin synthesis as a function of mineralization. An ACAS570, laser cytometer revealed that after one week of culture fibronectin caused the osteoblasts to adhere securely to the HAP surface. In addition, type I and type III collagen were synthesized after about two to three weeks. Synthesis of the extracellular matrix and subsequent mineralization were both substantially enhanced in the culture cells around of the HAP. These results suggest that the HAP implant surface may act as a substrate to permit cell growth that improves bone formation at bone defects.

• 大阪歯科学会の論文
• 1992-12-25

著者

• 池田 賀剛

  大阪歯大・大学院・歯周病

関連論文

• 1 人工骨移植材のヒト骨芽細胞様細胞に対する親和性 (第419回 大阪歯科学会例会)

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