Finding the Target Site of Chloroacetamides:A Thorny Subject(〔日本農薬〕学会賞受賞論文)

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概要

• 論文の詳細を見る

• Experimental approaches are described to find the primary mode of action of chloroacetamides using the microalga Scenedesmus as a model system. The data corroborate lipid metabolism as the target domain, particularly the processing of fatty acids. Incorporation of labeled oleic acid into a non-soluble cell-wall residue was found to be severely inhibited by chloro-and oxyacetamides with I_<50> values down to 10^<-8> molar. A quantitative rapid assay on acetamide activity based on this ^<14>C-oleate incorporation was developed which correlated with phytotoxicity. Herbicidally active S-enantiomers exhibited activity in the new assay, not the R-forms.

• 日本農薬学会の論文
• 1997-08-20

著者

• Boger Peter

  Department Of Plant Physiology And Biochemistry University Of Konstanz

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• Finding the Target Site of Chloroacetamides:A Thorny Subject(〔日本農薬〕学会賞受賞論文)

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