NDA, a red-pigment derived from ascorbic acid, induced micronuclei in mouse bone marrow hematopoietic cells

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概要

• 論文の詳細を見る

• NDA(2, 2'-nitrilodi-2(2')-deoxy-ascorbic acid monoammonium salt), a red-pigment synthesized by the reaction of dehydroascorbic acid with L-phenylalanine, induced micronucleated polychromatic/normochromatic erythrocytes(MNPCEs/MNNCEs)in ddY mouse bone marrow. Six male mice per group were intraperitoneally injected with red-pigment two times at 24h intervals and the bone marrow cells were examined 6h after the last treatment. Statistically significant increase of MNPCEs or MNNCEs was observed in all treatment groups.

• 日本環境変異原学会の論文
• 1998-07-21

著者

• Omura Hirohisa

  Faculty Of Agriculture Kyushu University

• Nonaka Michiko

  Faculty Of Agriculture Kyushu University

• Mitsuiki Masata

  Food Research & Development Laboratory, Ajinomoto Co.Inc.

• Kodama Tetsushi

  Tokyo Office, Nikka Whiskey Co.Inc.

• Kodama Tetsushi

  Tokyo Office Nikka Whiskey Co.inc.

• Mitsuiki Masata

  Food Research & Development Laboratory Ajinomoto Co.inc.

関連論文

• NDA, a red-pigment derived from ascorbic acid, induced micronuclei in mouse bone marrow hematopoietic cells
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