TWO-STAGE TESTING TO ESTABLISH NON-INFERIORITY IN THE STRATIFIED 2×2 CONTINGENCY TABLES

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概要

• 論文の詳細を見る

• In this article we propose a two-stage testing procedure for demonstrating noninferiority of a test drug in stratified 2×2 contingency tables, which includes a preliminary test of homogeneity of odds ratios. In order to prove that a new drug is not inferior to a control by more than a prescribed amount, we use model-based methods such as the weighted least-square (WLS) procedure by Grizzle et al. (1969), and test the null hypothesis of a specified non-unity ratio. Also included are some results of a Monte Carlo study conducted to investigate the accuracy of the proposed test to the null distribution, and power of the test under small and moderate sample size configurations.

• 日本計算機統計学会の論文

著者

• Tsujitani M

  Osaka Electro-communication Univ. Osaka Jpn

• Tsujitani Masaaki

  Department Of Engineering Informatics Osaka Electro-communication University

• Koshimizu Takashi

  Graduate School Of Engineering Osaka Electro-communication University

関連論文

• PROPERTY OF THE RC(M) ASSOCIATION MODEL AND A SUMMARY MEASURE OF ASSOCIATION IN THE CONTINGENCY TABLE
• Nonlinear Discriminant Analysis Using Feed-forward Neural Networks : An Application to Diabetes Classification
• TWO-STAGE TESTING TO ESTABLISH NON-INFERIORITY IN THE STRATIFIED 2×2 CONTINGENCY TABLES
• ASSOCIATION MODELS WITH LOCATION AND DISPERSION SCORES FOR THE ANALYSIS OF SINGLY-ORDERED CONTINGENCY TABLES

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