Desynchronization by Means of a Coordinated Reset of Neural Sub-Populations : A Novel Technique for Demand-Controlled Deep Brain Stimulation

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概要

• 論文の詳細を見る

• The coordinated reset of neural sub-populations is introduced as an effectively desynchronizing stimulation technique. For this, short sequences of high-frequency pulse trains are administered at different sites in a coordinated way, i.e. separated by suitable fixed delays. Desynchronization is effectively maintained by performing a coordinated reset with demand-controlled timing or by periodically administering resetting high-frequency pulse trains of demand-controlled length. Unlike previously developed methods, this novel approach is robust against variations of model parameters, and does not require time-consuming calibration. I suggest the novel technique to be used for demand-controlled deep brain stimulation in patients suffering from Parkinson's disease or essential tremor. Furthermore, the novel stimulation method might even be applicable to diseases with intermittently emerging synchronized neural oscillations like epilepsy.

• 理論物理学刊行会の論文
• 2003-09-30

著者

• Tass Peter

  Institute Of Medicine Research Centre Julich:department Of Stereotaxic And Functional Neurosurgery U

• Tass Peter

  Institute Of Medicine Research Centre Julich

関連論文

• Inferring Asymmetric Relations between Interacting Neuronal Oscillators
• Inferring Asymmetric Relations between Interacting Neuronal Oscillators
• Desynchronization by Means of a Coordinated Reset of Neural Sub-Populations : A Novel Technique for Demand-Controlled Deep Brain Stimulation
• Desynchronization by Means of a Coordinated Reset of Neural Sub-Populations : A Novel Technique for Demand-Controlled Deep Brain Stimulation
• Stochastic Phase Resetting : A Theory for Deep Brain Stimulation

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