インターフェロン療法をうけたC型慢性肝炎患者のカルテ調査から見た副作用の検討および患者説明用パンフレットの作成

概要

論文の詳細を見る
The side effects were determined based on medical reports from 17 patients with chronic hepatitis type C who were admitted to a hospital in order to receive interferon (IFN) therapy. A pamphlet to explain the side effects was made by referring to the results of this investigation at the same time. All patients complained of fever. Two patients stopped the IFN therapy. In addition, the follow side effects have been reported in the literature; arthralgia, muscular pain, digestive system symptoms, eruptions, and sleeplessness. By investigating the period and length of time for such side effects caused by IFN therapy, we found a large number of side effects with the most frequent being fever due to IFN treatment. The occurrence of slight fever and general fatigue was immediately after IFN medication and tended to continue for a long period of time. The fever and the malaise reappeared after a fixed period during this investigation. Our findings helped us to accurately describe the side effects. In particular, patients undergoing long term IFN treatment tend to develop unique side effects. In conclusion, patients treated with IFN need to clearly understand what side effect, they can expect to experience during the course of therapy.
2003-02-10