2次元NMR法で決定したEGFの立体構造
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概要
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The three-dimensional structures of mouse epidermal growth factor (53 residues) in pH 2.1 and pH 6.8 solutions were determined by two-dimensional NMR and distance geometry calculation. Ten structures that satisfied the NMR-derived distance constraints were obtained for each pHs using XPLOR program. The topology of the main chain was identical at both pHs, but the global shape at pH 6.8 was found to be more compact than that at pH 2.1.
- 日本生物物理学会の論文
- 1990-05-25