染色体接着因子コヒーシンの機能を中心とした染色体分配の分子メカニズム
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概要
- 論文の詳細を見る
Sister chromatid cohesion is established during DNA replication and maintained until metaphase in mitosis, when sister kinetochores are captured by microtubules associated with opposite poles of the spindle. The sister cohesion is released on anaphase thereby chromosome segregation brings about. Proteins needed for sister chromatid cohesion, named cohesins, were discovered and the regulation of cohesion has been revealed. We now better understand the molecular mechanism of chromosome segregation.
- 日本生物物理学会の論文
- 2000-09-25