恐慌性障害と僧帽弁逸脱症候群との臨床的関連について
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概要
- 論文の詳細を見る
As the biological research about anxiety disorders has been progressing mainly in the United States, the relationship between panic disorder (PD) and mitral valve prolapse (MVP) has been discussed in many reports. But as the complication rate varies from 0% to 60%, clinical estimation is not yet decided. In Japan there are only a few reports on this matter. We investigated the clinical relationship between PD and MVP on PD out-patients visiting our department. There were 30 patients, 12 men and 18 women, who were diagnosed as PD according to DSMiii-R. Their average age was 44.9 years old. Of the 30 patients, 12 patients, 4 men and 8 women, have been coming to our department since before. Other 18 patients, 8 men and l0 women were new-comers who had panic attacks consisting of palpitation, dizziness, chest discomfort, dyspnea and so on. 25 of the 30 patients visited other hospital or were consulting with other departments of our hospital, especially of internal medicine, before visiting our department. None of them showed organic abnormality after physical examination, ECG and blood chemistry. Cardioangiologists made diagnosis of MVP by use of tomographic UCG without the information about psychiatric diagnosis. The criteria of MVP were as follows, either of mitral valve leaflets prolapses to left atrium beyond the line of mitral ring, or the anterior leaflet and the posterior leaflet of mitral valve don't connect tightly. As a result, none of the 30 PD patients were diagnosed as MVP according to both criteria mentioned above. None of them showed cardiac dysfunction on UCG. It is said that about 5% of normal population was diagnosed as MVP by use of UCG, but we couldn't find that PD patients had MVP at a high rate. We concluded that the clinical relationship between PD and MVP is weak and not significant.
- 日本心身医学会の論文
- 1993-08-01