うつ病における指尖容積脈波に関する研究
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概要
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The study on the function of the autonomic nervous system was performed chiefly by the digital plethysmogram in 37 normal adults and 66 depressive patients. First each subject was studied on both psychic and physical signs by Hamilton rating scale, Beck depression inventory, and Abe's list of autonomic nervous signs. Next such physical tests as Aschner's test, CzermakHering's test, Schellong's test, and Cold pressor test were examined. Thirdly such studies as the digital plethysmogram (PTG), the electrocardiogram (ECG), and the respiration curve by means of the polygraph were examined on each subject. The part of depressive patients was reexamined in the remissive period by the same procedure in the depressive phase. Several parameters (patterns, height, t", t', Dl, and B) of some waves of the plethysmogram were analysed. And also, the mean (M) standard deviation (SD), and coefficient of variation (CV= SD/M×100) of the continuous 100 heart beats were analysed. The positive results are as follows : l) Sclerotic pattern of PTG was seen more often in depressive subjects than in normal adults. 2) The height of PTG at rest, at 5 min., and 10 min. after standing in the depressvie was significantly lowered than in the normal. 3) CV of the continuous RR intervals on ECG at rest and at 10 min. after standing in the depressive was significantly lowered than in the normal. 4) Although the average of heart beat in the depressive, at rest, not significantly differed from that in the normal in each age except 20's, it significantly differed in 20's, 40's, and 50's at 10 min. after standing. 5) The height of PTG of the Group B which had more autonomic complaints was significantly lowered than the group A which had less complaints both at rest and after standing. 6) The height of PTG and CV of the continuous RR intervals were more significantly heightened on the remissive period than on the depressive phase. Therefore, it was suggested that the sympathetic function of the depression was exaggerated because of exciting mode by Yoshimura in PTG, to which the above results were ascribed, and that the secondary hypofunction of parasympathetic system attended on the depression because of the lowered CV of the RR ' t I the results shown above And it was shown merva as. especially from the results of PTG that the function of the autonomic nervous system was well connected with physical signs, the former being recovered as the latter disappeared in depression.
- 日本心身医学会の論文
- 1988-10-01