放射線照射によるマウス顎下腺組織の形態的変化に関する実験的研究 : 放射線学的所見と病理組織学的所見の比較検討を中心に

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The morphological changes of submaxillary glands irradiated by X-ray radiation were examined by salivary gland scintigraphy with ^<99m>TcO_4 and angiography, and the observations were compared with pathological findings. The results obtained were as follows: 1) The submaxillary gland images obtained after irradiation gradually reduced in size, and the accumulation of ^<99m>TcO_4 per unit area gradually increased. 2) Histologically, irradiated tissue showed mild atrophy of the acinus and granular convoluted tubules. 3) The vascular system of submaxillary gland irradiated by X-ray radiation showed only little change, and there was no relationship between the vascular changes and scintigraphic findings. 4) Histological findings showed that the effect of irradiation on the mouse salivary glands were small, like the microsialograohic findings. 5) In conclusion, it was shown that scintigraph showed morphological changes even with the slight histological changes.
1993-06-30