経過中に一過性高ビリルビン血症を呈したネフローゼ症候群の2例

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概要

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• We present two patients with idiopathic nephrotic syndrome who showed temporary indirect hyperbilirubinemia during the course of treatment with immunosuppressant drugs and/or steroids. We analyzed the gene of the bilirubin uridine-diphosphate glucuronosyltransferase (B-UGT) and found that patient 1 was a compound heterozygote for the G71R and T-3263G mutations and patient 2 was a heterozygote for the G71R mutation. Hyperbilirubinemia should be considered as one of the adverse effects of immunosuppressant drugs and/or steroids in patients carrying the polymorphic mutations of the B-UGT gene.

• 山形大学の論文
• 2004-02-16

著者

• 梁 麗俊

  山形大学医学部

関連論文

• 経過中に一過性高ビリルビン血症を呈したネフローゼ症候群の2例

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