An Angiotensin Receptor Blocker and Spironolactone Enabled A Withdrawal from Furosemide and KCl in A Patient with Pseudo-Bartter's Syndrome
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概要
- 論文の詳細を見る
A 30-year-old woman with pseudo-Bartter's syndrome was referred to our department because of hypokalemic symptoms caused by outrageous abuse of furosemide and by KCl infusion administered to compensate for it. As an attempt to break this vicious cycle, we first tried to change furosemide with azosemide, a long-lasting loop diuretics, to avoid acute excessive diuresis and excretion of potassium. Administration of losartan effectively attenuated the concentration of extremely activated plasma aldosterone. Administration of spironolactone reduced aldosterone breakthrough induced by losartan and the patient was released from both furosemide and KCl. Blocking renin-angiotensin-aldosterone system demonstrated to be an effective treatment for pseudo-Bartter's syndrome by the improvement of the total body potassium level which was decreased before treatment.
- 長崎大学の論文
著者
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Ashizawa Naoto
Division Of Cardiovascular Medicine Department Of Translational Medical Sciences Course Of Medical A
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Ashizawa Naoto
Division Of Cardiovascular Medicine Nagasaki University Graduate School Of Biomedical Sciences
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