トリチウムの体内動態と最近の話題 : アイソトープ作業者の安全教育のために

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For safety handling of tritium, a brief-review is made of tritium intake and its metabolism in the body, as well as its elimination. After ingestion or inhalation of tritiated water (HTO), the biological half life of tritium in the body fluid is about 10 days in human subjects. The intake of HTO through the lungs is rapid and almost complete. In the case of low level tritium gas (HT), tritium intake through the skin is extremely low. In contrast, significant tritium intake occurs through the skin which is in touch with metals whose surfaces are already contaminated with tritium and the biological half-life would thus become longer. Intaken HT is oxidized to HTO by intestinal anaerobic becteria. The oxidation rate of HT in man is estimated to be 0.86μCi HTO/l body fluid/HR per 1μCi HT/ml ambient air. Tritium content in the body exposed to HTO vapor is 15000 times than that exposed to HT in the same tritium content in ambient air. In the case of accidental intake of tritium, excretion of tritium is accelerated by either oral intake of 3-4 liter water per day in form of juice, tea, coffee and beer, or by intravenous injection of 5% glucose or Ringer`s solution
富山大学の論文