磁石の人体に及ぼす影響特に組織培養法によるSm-Co_5磁石の細胞学的研究

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Tne cytotoxicity of the Sm-Co_5 magnet was assayed by the tissue culture of two species of strain cells which were cultivated in the presence of this magnet and its components, and the magnetic field ; the growth rates and the morphological changes of FL cells, and the karyotype of WI-38 cells were employed as criteria for the cytotoxicity in comparison with the findings of the control cells. Sm, Sm-Co_5 alloy non-magnetized, Sm-Co_5 magnet caused no detectable or no definite cytotoxic effects which were the inhibition of cell growth and the morphological changes of FL cells. Meanwhile, Co showed high cytotoxicities to FL cells ; each of them induced the inhibition of cell growth, and rounding of cell accompanied with lysis and collapse. The magnetic field of Sm-Co_5 magnet as well as that of Sm-Co_5 alloy non-magnetized induced no chromosomal aberrations over the upper limit of acceptability. These findings support the adaptability and no cytotoxicity of Sm-Co_5 magnet to the human body.
1985-09-10