Transmission of Japanese Encephalitis (JE) Virus in Gia Luong District, Ha Bac Province, Vietnam, After Je Vaccination, 1993-1994

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概要

• 論文の詳細を見る

• A total of 15,183 children under 10 years old (37% of target population) was immunized with JE vaccine in Gia Luong District, Ha Bac Province, Vietnam, in 1993 to 1994. JE virus transmission was investigated by swine antibody survey and virus isolation from field mosquitoes. By the hemagglutination inhibition (HI) test, 73-90% of swine were antibody positive all year round, with high geometric mean titer (GMT) of 92.67-95.14 in May and June. By suckling mouse brain inoculation, 6 JE virus strains were isolated from Culex tritaeniorhynchus and Cx. vishuni, as well as laboratory reared F1 from field-caught Cx. tritaeniorhynchus. Serodiganosis by IgM-capture ELISA (MAC-ELISA) carried out on 60 of 85 clinical encephalitis cases detected 43 positives (71.66%). All these serologically confirmed JE cases had not been vaccinated. The results supported the vaccine efficacy to prevent overt JE.

• 長崎大学の論文

著者

• Nga Phan

  National Institute Of Hygiene And Epidemiology

• Phuong Le

  ベトナム

関連論文

• Transmission of Japanese Encephalitis (JE) Virus in Gia Luong District, Ha Bac Province, Vietnam, After Je Vaccination, 1993-1994

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