ケロウジ (Sarcodon scabrosus) 培養菌糸体に含まれる新規カサン骨格ジテルペノイド

概要

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We had isolated the cyathane diterpenoid named sarcodonins from the fruiting body of fungus Sarcodon scabrosus. These compounds showed diversity of biological activities such as bitter taste, antibacterial activity and anti-inflammatory activity. With the objective of the mass production of these sarcodonins, we cultured the mycelium of this fungus. From the mycelium of this fungus, we isolated ergosterol (１) and ergosterol peroxide (３) along with a new cassane diterpenoid named sarcolide A (cassa-14-（17）,15-diene-1,5-dihydroxy-3,4-carbolactone), while we did not found any cyathane diterpenoids. The mycelium of S. scabrosus did not produce any sarcodonins in the culture condition.
信州大学の論文